重組人卵泡刺激素(FSH)說明
目錄編號：HOR-253
中文名稱：重組人卵泡刺激素(FSH)
英文名稱：Recombinant Human Follicle Stimulating Hormone
重組人卵泡刺激素(FSH)序列號:
重組人卵泡刺激素(FSH)(FSH)簡介:
Follicle Stimulating Hormone Human Recombinant is a glycoprotein having a total molecular mass of 30，000 Dalton. FSH is a heterodimeric hormone consisting of 92 amino acids a chain and 111 amino acids b chain. The FSH is purified by proprietary chromatographic techniques.
重組人卵泡刺激素(FSH)背景:Follicle stimulating hormone （FSH） is a hormone synthesised and secreted by gonadotropes in the anterior pituitary gland. FSH and LH act synergistically in reproductionIn women， in the ovary FSH stimulates the growth of immature Graafian follicles to maturation. As the follicle grows it releases inhibin， which shuts off the FSH production.
In men， FSH enhances the production of androgen-binding proteinby the Sertoli cells of the testes and is critical for spermatogenesis.
In both males and females， FSH stimulates the maturation of germ cells. In females， FSH initiates follicular growth， specifically affecting granulosa cells. With the concomitant rise in inhibin B FSH levels then decline in the late follicular phase. This seems to be critical in selecting only the most advanced follicle to proceed to ovulation. At the end of the luteal phase， there is a slight rise in FSH that seems to be of importance to start the next ovulatory cycle.
Like its partner， LH， FSH release at the pituitary gland is controlled by pulses of gonadotropin-releasing hormone（GnRH）. Those pulses， in turn， are subject to the estrogen feed-back from the gonads.
來源宿主：Chinese Hamster Ovary cells
產(chǎn)品規(guī)格：
溶解建議：
提供的重組人卵泡刺激素產(chǎn)品為白色無菌凍干粉末.推薦使用無菌的18MΩ的超純水來溶解，濃度不低于100ug/ml，便于后續(xù)稀釋.
穩(wěn)定性說明：
Lyophilized recombinant FSH although stable at room temperature for 3 weeks， should be stored desiccated below -18℃. Upon reconstitution FSH should be stored at 4℃ between 2-7 days and for future use below -18℃. For long term storage it is recommended to add a carrier protein （0.1% HSA or BSA）. Please prevent freeze-thaw cycles.
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