人內(nèi)皮素2(EDN2)說(shuō)明
目錄編號(hào):HOR-308
中文名稱(chēng):人內(nèi)皮素2(EDN2)
英文名稱(chēng):Human Endothelin-2
人內(nèi)皮素2(EDN2)序列號(hào):
Cys-Ser-Cys-Ser-Ser-Trp-Leu-Asp-Lys-Glu-Cys-Val-Tyr-Phe-Cys-His-Leu-As p-Ile-Ile-Trp.
人內(nèi)皮素2(EDN2)簡(jiǎn)介:
EDN2 contains 21 amino acids having a molecular mass of 2546.97 Dalton.
人內(nèi)皮素2(EDN2)背景:
via the MAPK pathway: p44 and p42 are phosphorylated when THP-1 cells are stimulated with EDN2. Migration to EDN2 is inhibited by hypoxia and by pertussis toxin. EDN2 leads to activation of macrophages. EDN2 shares a similar peptide sequence with chemokines and may signal via a similar receptor and MAPK-mediated pathway. Furthermore, EDN2 expression by tumors may modulate the behavior of macrophages such that activated cells accumulate in areas of hypoxia.
來(lái)源宿主:
產(chǎn)品規(guī)格:
溶解建議:
提供的人內(nèi)皮素2產(chǎn)品為白色無(wú)菌凍干粉末,凍干粉里不含有其它添加劑.推薦使用無(wú)菌的18MΩ的超純水來(lái)溶解,濃度不低于100ug/ml,便于后續(xù)稀釋.
穩(wěn)定性說(shuō)明:
Lyophilized EDN2 although stable at room temperature for 3 weeks, should be stored desiccated below -18℃. Upon reconstitution EDN2 should be stored at 4℃ between 2-7 days and for future use below -18℃. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles.
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