人內(nèi)皮素3(EDN3)說明
目錄編號(hào)：HOR-309
中文名稱：人內(nèi)皮素3(EDN3)
英文名稱：Human Endothelin-3
人內(nèi)皮素3(EDN3)序列號(hào):
Cys-Thr-Cys-Phe-Thr-Tyr-Lys-Asp-Lys-Glu-Cys-Val-Tyr-Tyr-Cys-His-Leu-As p-Ile-Ile-Trp.
人內(nèi)皮素3(EDN3)簡介:
EDN3 contains 21 amino acids having a molecular mass of 2634.1 Dalton.
人內(nèi)皮素3(EDN3)背景:
EDN3 interacts with endothelin receptor B， on the surface of cells. Throughout embryonic development， EDN3 takes part in neural crest cells that migrate from the developing spinal cord to specific regions in the embryo， where they give rise to many different types of cells. EDN3 and EDN3R are necessary for the formation of nerves in the large intestine （enteric nerves） and melanocytes （produce melanin）. Mutations in the EDN3 gene is linked with Waardenburg syndrome， type IV that is characterized by changes in skin， hair， and eye coloring. Mutations in the EDN3 gene is linked with Hirschsprung disease that causes severe constipation or intestinal blockage.
來源宿主：
產(chǎn)品規(guī)格：
溶解建議：
提供的人內(nèi)皮素3產(chǎn)品為白色無菌凍干粉末，凍干粉里不含有其它添加劑.推薦使用無菌的18MΩ的超純水來溶解，濃度不低于100ug/ml，便于后續(xù)稀釋.
穩(wěn)定性說明：
Lyophilized EDN3 although stable at room temperature for 3 weeks， should be stored desiccated below -18℃. Upon reconstitution EDN3 should be stored at 4℃ between 2-7 days and for future use below -18℃. For long term storage it is recommended to add a carrier protein （0.1% HSA or BSA）. Please prevent freeze-thaw cycles.
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